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Arimidex (Anastrozole)

  • Raw Material: Anastrozole
  • Manufacturer:Astra Zeneca
  • Package: 28 tabs x 1mg/tab

Use:  Aromatase Inhibitor 

Dosage: 0,25 mg - 1mg / day

Period:  during cycle & post cycle therapy (PCT)

Anastrozole (also known as Arimidex, Aridex, ARI) is a non-steroidal aromatase-inhibiting drug, medically used and approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. 

Anastrozole works by inhibiting the synthesis of estrogen up to 80% !! It inhibits the enzyme aromatase, which is responsible for converting androgens to estrogen. 

The drug is appropriately used when using substantial amounts of aromatizing steroids or when one is prone to gynecomastia and using moderate amounts of such steroids. Anastrozole does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much more so than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.

As an aromatase inhibitor, Anastrozole's mechanism of action -- blocking conversion of aromatizable steroids to estrogen -- is in contrast to the mechanism of action of anti-estrogens such as Clomiphene (Klomen) or Tamoxifen (Nolvadex, Tadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others. During a cycle, if using Arimidex, there is generally no need to use Klomen as well, but there may still be benefits to doing so.

Literature provided by the original maker of Anastrozole (Arimidex, produced by Zeneca Pharmaceuticals) states that stable blood plasma concentrations of the compound are achieved after a mere 7 consecutive daily doses.

It can be used during  the cycle as well as for the post cycle therapy. Normal use is 0,5 - 1 mg all 3 days for a lower dosed steroid cycle  up to max. 1 mg/day for professional athletes while competing.

As a guideline the dosage is 0,5-1mg every second day for a 500-750mg/week testosteron cycle. In the Post-Cycle-Therapy 0,5 mg / day are used.

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